A study conducted by Rhode Island Hospital aims to detect early brain changes in Alzheimer’s disease using saliva specimens. The hospital’s Alzheimer’s Disease and Memory Disorders Center is currently recruiting participants for its ExosomeAD study, a multi-year collaboration between researchers at Rhode Island Hospital and Brown University that was funded by a grant from the National Institutes on Aging. The study involves recruiting people with normal cognitive functioning, mild cognitive impairment, and mild dementia due to Alzheimer’s. The testing involves the collection of saliva samples, and researchers are hoping to get a strong signal since there is a higher concentration of exosomes coming from the brain in saliva. If successful, this test could open new possibilities for early diagnosis of Alzheimer’s disease. The center is actively seeking participants aged 65 years and older for the study.